Plumbago zeylanica (scientific name: Plumbago zeylanica) is a perennial plant of the Plumbaginaceae family found in tropical and subtropical regions. It has long been used in Ayurveda as "Chitraka," and has traditionally been used for stomach health, blood circulation support, skin care, and other purposes. The roots contain characteristic naphthoquinone compounds, and are known as irritating plants.
In terms of components, plumbagin , flavonoids, phenols, glycosides, etc. have been identified as representative active ingredients. Based on these components, multifaceted physiological activities such as anti-inflammatory , antioxidant , antibacterial/antifungal , cell growth regulation , and antitumor have been reported, mainly at the basic research level.
Furthermore, in a joint research project between our company and the Yokohama City University Longevity Science Laboratory, it has been confirmed that this plant extract promotes the proliferation of hair papilla cells , suppresses indicators of cell aging (anti-aging effect) , and inhibits 5α-reductase activity . These effects suggest that it may be applicable to hair growth and regrowth as well as AGA countermeasures by improving the scalp environment and maintaining hair follicle function.
Additionally, other research reports suggest that, due to the effects of plumbagin and other compounds, it may also have other effects such as antiparasitic (e.g., protozoan and helminthic) properties, support for glucose metabolism (blood sugar regulation) , and support for liver function (liver protection) .
Characteristics of Indian matsuri
- Scientific name: Plumbago zeylanica
- Classification: Plumbaginaceae, Pine genus
- Other names: Ceylon pine, Chitraka, Ceylon leadwort (English name)
- Appearance: A perennial plant with small white flowers and long, narrow leaves.
- Distribution: Tropical to subtropical regions, mainly India
- Parts used: Mainly roots (traditional use)
Expected effects
- Promoting proliferation of dermal papilla cells: Joint research between our company and the Yokohama City University Longevity Science Laboratory suggests that this product may promote the proliferation of dermal papilla cells, which are involved in the growth of hair follicles.
- Anti-aging (maintenance of cell function) effect: It has been suggested that it may contribute to maintaining healthy cell function by suppressing cellular aging markers.
- 5α-reductase inhibitory effect: It has been suggested that this drug may suppress the activity of the enzyme involved in the conversion of testosterone to DHT, which may be involved in the mechanism related to male pattern baldness (AGA).
- Supports hair growth and hair environment: The synergistic effects mentioned above suggest the possibility of application in hair growth and maintaining hair condition through the improvement of the scalp environment and hair follicle function.
- Anti-inflammatory effects: It has been suggested that it may contribute to reducing inflammatory responses by regulating inflammatory mediators and cytokines.
- Antioxidant effect: It has been suggested that it may contribute to reducing oxidative stress associated with reactive oxygen species (ROS) and protecting cells.
- Antibacterial and antifungal effects: It has been reported to have growth inhibitory activity against some bacteria and fungi.
- Antiparasitic effect: There are reports suggesting that it reduces the survival rate and inhibits the growth of protozoa and helminths.
- Antitumor effects: It has been reported that it inhibits cell proliferation and induces apoptosis in multiple cancer cell lines.
- Anti-diabetic (supports glucose metabolism) effect: Basic research suggests improvement in indicators related to blood sugar levels and insulin sensitivity.
- Liver function support (hepatoprotection): In a hepatocellular injury model, it has been suggested that this compound may contribute to reducing oxidative stress and maintaining liver enzyme balance.
